RNA-Seq bioinformatics analysis video tutorial

I often spend some time on Rafael Irizzarry's youtube channel, that is provided with very useful and clear video tutorials and insights on bioinformatics and statistics. In this video- tutorial, a farily explanatory introduction to RNA- Seq data analysis is perfromed by Kasper Hansen, who gives an introduction to RNAseq and relevant computational and statistical … Continue reading RNA-Seq bioinformatics analysis video tutorial

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NGS and data analysis for epigenetics. A couple of reviews to take stock of the situation.

Epigenetic regulation of DNA is a point of growing interest. If many evidences lead to the idea that genotype and phenotype are linked in a very complex relationship, the genome architecture is the main player in this puzzling game affecting gene frequencies. Both 3D arrangement of chromatin, and the disposition of nucleosomes along the DNA, have … Continue reading NGS and data analysis for epigenetics. A couple of reviews to take stock of the situation.

Biotech Corporations: Illumina announces NextBio acquisition.

I republish almost on real time the announcement of one of the biggest transactions in the biotech corporate world in 2013. Right about three minutes ago, the headquarters of Illumina announced the acquiring of NextBio, leader in the field of biological BigData services. Illumina, founded in 1998 and accounted for more than 300 millions dollars … Continue reading Biotech Corporations: Illumina announces NextBio acquisition.

Is Whole Genome Sequencing more performing than classical Genotyping?

Ask a german researcher and he may answer “yes, it is”, expecially if the german researcher you question is Stefan Niemann from the Molecular Mycobacteriology Department of the Forschungszentrum Borstel Institute in Sülfeld, Germany. Niemann’s team primary aim was to find a SNP-based distinction able to classify different Mycobacterium tuberculosis strains.  They considered 86 different strains of M. tuberculosis isolated … Continue reading Is Whole Genome Sequencing more performing than classical Genotyping?