The paper I am going to explore today introduces MethylMix, an R package designed to identify DNA methylation-driven genes. DNA methylation is one of the processes that are more extensively studied in biomedicine, since it has been found as a principal mechanism of gene regulation in many diseases. Although high-throughput methods are able to produce … Continue reading MethylMix: an R package for identifying DNA methylation-driven genes
Epigenetic regulation of DNA is a point of growing interest. If many evidences lead to the idea that genotype and phenotype are linked in a very complex relationship, the genome architecture is the main player in this puzzling game affecting gene frequencies. Both 3D arrangement of chromatin, and the disposition of nucleosomes along the DNA, have … Continue reading NGS and data analysis for epigenetics. A couple of reviews to take stock of the situation.