MethylMix: an R package for identifying DNA methylation-driven genes

The paper I am going to explore today introduces MethylMix, an R package designed to identify DNA methylation-driven genes. DNA methylation is one of the processes that are more extensively studied in biomedicine, since it has been found as a principal mechanism of gene regulation in many diseases. Although high-throughput methods are able to produce … Continue reading MethylMix: an R package for identifying DNA methylation-driven genes

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The Oncodrive suite. Bionformatics methods to detect driver mutations in cancer.

One of the most amazing groups whose work I have recently explored, is based in the rapidly- growing young UPF university in Barcelona. The Biomedical Genomics Group applies its high computational expertise to cancer research, focusing on the identification of those mutations that are actually involved in determining the tumor phenotype, the so- called driver mutations. The … Continue reading The Oncodrive suite. Bionformatics methods to detect driver mutations in cancer.